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Genetic ablation of calcium-independent phospholipase A2β causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine.

Date 2nd Jul '12
Author(s) Hans H. Dietrich, Dana R. Abendschein, Sung Ho Moon, Neema Nayeb-Hashemi, David J. Mancuso, Christopher M. Jenkins, Kevin M. Kaltenbronn, Kendall J. Blumer, John Turk, and Richard W. Gross.
Journal Am J Physiol Heart Circ Physiol, Jun 2010; 298: H2208 - H2220.

Method Extract

... ...25 m of thin-walled silicone tubing in a flask gassed with 95%O2-5% CO2. The solution was heated to 37C (Radnoti heat exchanger; Radnoti, Monrovia, CA) before being dripped on the exposed vessels. One of the dissected vessels was located at 40... ...

Keywords Radnoti heat exchanger, mesenteric arteries, endothelium, contractility
Our Ref: 1886
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