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Targeted transgenesis reveals discrete attenuator functions of GRK and PKA in airway β2-adrenergic receptor physiologic signaling.

Date 2nd Jul '12
Author(s) Wayne C. H. Wang, Kathryn A. Mihlbachler, Alicyn C. Brunnett, Stephen B. Liggett.
Journal PNAS, 2009 (106) 35 15007-15012.

Method Extract

... ...Tracheal Ring Studies. Excised trachea were dissected free of surrounding tissue and cut to 5-mm cross-sections. These were studied with an ex vivo isometric myograph system (Radnoti) (15, 16). Briefly, rings were maintained in a bath of physiologic... ...

Keywords isometric, myograph, smooth muscle
Our Ref: 1688
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